Mechanobiology instruments
Measuring the mechanics of living tissue models.
Aurenix Biosciences is developing a magnetic tweezers platform that applies controlled forces to 3D tissue models and maps how they respond. We are starting with organoids, giving research teams a mechanical readout alongside imaging and omics.
Talk to us about a pilotWhy mechanics
Stiffness and viscoelasticity shape how cells grow, differentiate and respond to treatment. Yet most tissue models are characterised by what they look like and what they express, not by how they behave under force.
Active force application
Controlled, localised forces applied to the sample, rather than passive observation.
Spatial force mapping
Measurements across different regions of a 3D model, not a single bulk average.
Fits existing workflows
Designed as an add-on to standard inverted microscopes, so labs keep the imaging they already use.
Starting with organoids
Organoids are becoming central to drug discovery, but batch-to-batch variability is hard to see until it shows up in the data. We are building a mechanical quality-control readout for organoid workflows, for research use.
- Mechanical characterisation of organoid batches
- Target validation and mechanistic studies upstream of screening
- Pilot studies with research and pharma teams
Illustrative only: forces applied and measured at different regions of a 3D model.
Team
Engineers and biologists who have built and used force-measurement instruments in the lab.
Abhinav Kongari
Co-founder and CEO
PhD from UCL in magnetic tweezers instrumentation. Royal Academy of Engineering Enterprise Fellow. Leads instrument development and partnerships.
Andrea Balukova
Co-founder
Background in optical biology and nanomaterials. Leads biological assay development and sample workflows.
Supported by
Non-dilutive research funding, including a Royal Academy of Engineering Enterprise Fellowship.
Work with us
We are looking for early partners to run pilot studies on their own tissue models. If mechanics could help answer a question in your work, we would like to hear from you.
abhinav@aurenix.bio